MyTwin Longevity: from biological age to a personal longevity plan

According to the World Health Organization, global life expectancy was 71.4 years in 2021, and healthy life expectancy 61.9 years: close to ten years lived, on average, in less than full health. That gap is what longevity medicine works on, and what MyTwin Longevity is designed for.

The idea is to look early, while there is still room to act: measure where the body stands today, see which levers matter most for this person, and follow how things change over time. Our article on healthspan sorts what science really knows about living longer in good health.

The app lays the journey out in four steps. It starts with a health check-up: the blood biomarkers feed the twin, and the biological age appears once the check-up is done. Our article on the preventive health check-up explains what such a check-up covers.

The second step is a consultation of at least 30 minutes with a doctor specialised in prevention and longevity, from MyTwin’s network of partner doctors. The results are not left for the person to interpret alone: they are read with a doctor, who helps build the personal plan of the third step. New tests then update the twin, and the journey starts again.

MyTwin Longevity computes biological age with Phenotypic Age, or PhenoAge, a measure published in 2018. It combines chronological age with nine biomarkers found in a routine blood test, among them albumin, glucose, creatinine and C-reactive protein. In the original study, each additional year of Phenotypic Age was associated with a 9% higher risk of death, independently of chronological age, including among people who reported no disease.

A biological age is a signal, not a diagnosis. A single measurement is a snapshot; its value grows with repeated tests, which turn one number into a trajectory. That is why the journey loops back. Our article on biological age explains what the tests really measure, and what they don’t.

Biological age is the entry point. Around it, the app brings three more views from the MyTwin Engine:

• Organ-system scores for the main systems of the body, such as cardiovascular, respiratory and musculoskeletal health.
• Risk projections: how a risk may evolve over the coming years, using validated models wherever they exist, such as QFracture for fracture risk.
• What-if simulations: what would change under a concrete decision, such as losing weight or changing one’s lifestyle, projected from the effects measured in published trials.

Each score carries the reliability level the engine gives it, from a clinically validated model to a composite index of our own. Not every domain has a score yet: more will be added as the data and the evidence allow.